How to make the medicines more effective?
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One of the main problems of the effective action of drugs is that while they «travel» the body of the substances just destroyed our defense system. In addition, medications are often toxic and cause no little harm. Has long been developing targeted (that is directly to the site of the lesion) drug delivery. But what if the disease spread throughout the body, as is the case in viral diseases? The solution found by domestic scientists.
For the development of responsible experts from Tomsk Polytechnic University, First St. Petersburg state medical University named after academician I. P. Pavlov, in collaboration with the School of engineering and materials science, University of London Queen Mary (UK) and Institute of influenza Ministry of health of Russia. Joint invention is a purpose micro containers for medicinal substances. Thanks to this method, almost leveled the collapse of the therapeutic agents and the drug becomes much more effective that is able to significantly reduce seasonal morbidity.
This medication is very convenient for using form: it is injected into the nasal cavity in the form of a spray, and then the microcapsules are distributed in the nose and throat and enter the lungs. According to scientists, common substances active in the human body not more than an hour, after which they are destroyed. The microcapsules gradually release the drug, so the drug remains active during the day. As told in an interview with RIA Novosti Junior researcher of laboratory of new drug forms of the Centre of RASA on the basis of National research Tomsk Polytechnic University Alexander Thymine
«the containers are composed of polysaccharides and polypeptides. Is biodegradable polymers, which does not harm your body.
In purpose micro containers placed small interfering RNA, which can inhibit the H1N1 influenza. Due to the extremely high capacity of microcapsules is provided off the activity of genes of influenza virus by means of RNA interference, thus achieving a reduction of viral load.»
Now conducted preclinical testing of technology on animals. Thanks to the new universal platform will be possible the creation of complex drug that has antiviral effect against several strains of influenza and other respiratory viruses.
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