One of the most effective means of cancer treatment currently is chemotherapy. And for all its virtues it has a significant drawback: extremely high toxicity for the organism. But soon, as reported in the journal Angewandte Chemie, can be created a number of anticancer chemotherapeutic drugs with low toxicity. As scientists say, these drugs can be created using gold.
The Discovery belongs to experts from the University of Edinburgh (Scotland). The new method is to use the gold dust and silver nanoparticles in the "cooking" of the drug. The use of metal particles in drugs for the treatment in itself is not new. Over recent years there have been several studies on this topic. In some cases, the nanoparticles serve as a means for removal of the tumor, acting as a "guideline" for the drug which "extends" in place of neoplastic lesions. In other cases, the nanoparticles act as a means for drug delivery.
But Scottish scientists have discovered that these particles can be used also to enhance the action of substances. Experts drew attention to the fact that gold speeds up many reactions in the body. This observation led them to speculate that this property of nanoparticles can be used to create a new kind of chemotherapy that will only work in the presence of atoms or nanoparticles of gold. Thus, the human body can be separately introduce gold nanoparticles to deliver them to the tumor, and then the components of the medication, which will be "collected" directly from the lesion. This approach will eliminate the toxic effect of chemotherapy on the body as a whole. As stated by one of the authors of the study, Asher Uniti-Brochet
«We opened new chemical properties of gold, which I didn't before, and our experiments have shown that this metal can be used to very safe «enable» chemotherapy directly inside the tumor. In the future the device, introducing gold particles only in the tumor, can significantly reduce the strength of side effects to other parts of the body».
Based on materials of agencies of RIA "news"
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