First grown pigs whose organs can be transplanted to a human

Date:

2017-08-11 14:00:06

Views:

2835

Rating:

1Like 0Dislike

Share:

First grown pigs whose organs can be transplanted to a human Source:

As you know, animals whose organs can be transplanted to a man almost without fear, are not our closest «relatives» apes, and pigs. The truth that transplant organs has a big drawback: the presence in pigs is extremely dangerous for human retroviruses. But a group of scientists from the USA managed to cope with this problem and «humanize» animals, making their organs suitable for transplant.

It is fair to say that science knows of successful attempts to transplant organs from animals to humans, but the training required to conduct such operations extremely costly and difficult. Know-how of American specialists, according to the Agency RIA «news» citing the journal Science, greatly simplifies the procedure. According to one of the study's authors, George Church of Harvard University,

«the pig Organs are similar to their human counterparts in size and operating principles, and they can be grown in large numbers for transplantation. Now this is not done for two reasons – because of an incompatibility between pigs and humans at the level of the immune system and the possibility of human infection by retroviruses that are present in the DNA of the animal».

A large-Scale study was launched 2 years ago, when Mr. Church with his colleagues learned how to edit and delete parts of the DNA in the cells. It is to such forms are the so-called PERV-a proviruses that coexist with pigs for hundreds of thousands of years. They do not pose a threat to the animal, but, penetrating into the human body, together with a transplanted organ can cause serious health problems and complications.

The Main problem with these viruses is that they are not amenable to traditional methods of therapy, as embedded in pig DNA and the genome of the animal itself contains copies of the virus. To help scientists come editor CRISPR/Cas9. With the help of professionals cut out from the genome of the pig all 62 version of the PERV-a virus. Did the cells and organs of the animals «» and helped to avoid pre-existing complications.

In the course of work on the virus, scientists have developed a new technique of input CRISPR/Cas9 in cells of pigs, which prevented them «self-destruct» after the mass removal of large numbers of DNA, as well as to overcome many other problems associated with editing of the genome of the embryo.

Implantiruut «edited» the embryos into the womb of surrogate mothers, the scientists obtained three dozen healthy piglets whose organs were completely cleared from PERV. But scientists don't stop: the experts aims to eliminate another important drawback associated with the transplant: suppression of the immune system. If scientists will be able to create pigs whose organs will not be perceived by the immune system of the recipient as something alien, it may be a real breakthrough in medicine and transplantation.

Recommended

The coronavirus has mutated into 30 new strains

The coronavirus has mutated into 30 new strains

While coronavirus Apocalypse slowly but inevitably becomes routine, the virus SARS-CoV-2 continues to evolve. And, unfortunately, he was good at it. Writes , with reference to the South China Morning Post reports that new studies show that the virus ...

In the United States recognized that the ventilator dies 88% of patients with coronavirus

In the United States recognized that the ventilator dies 88% of patients with coronavirus

When the world is raging coronavirus that causes pneumonia and kills people, the only solution is intensive care. If this is not done, the victims will be very much. Today for severe patients there is only one solution — connected to the appara...

Can a transfusion of blood plasma to cure the coronavirus?

Can a transfusion of blood plasma to cure the coronavirus?

Typically, vaccination involves the introduction into the organism of the weakened or killed microorganisms (viruses) designed to create a strong immunity to possible future infectious diseases — that is, for selection of antibodies. But what i...

Comments (0)

This article has no comment, be the first!

Add comment

Related News

Found a way to

Found a way to "reprogram" cells to treat diseases

for anybody not a secret that cells in our bodies have a "built-in" ability to confront various negative factors. But, unfortunately, not always this convenient feature allows you to fully "beat attack". Then come to the aid of va...

Developed a cure for cancer based on gold

Developed a cure for cancer based on gold

One of the most effective means of cancer treatment currently is chemotherapy. And for all its virtues it has a significant drawback: extremely high toxicity for the organism. But soon, as reported in the journal Angewandte Chemie...

In Germany may allow to treat the disease parasitic worms

In Germany may allow to treat the disease parasitic worms

According to some research (which the scientific community agrees), some diseases like allergies, type I diabetes, and several autoimmune processes can arise from the fact that the human body from childhood «well protected...

Created a biosensor that stimulates the secretion of sweat when the person is relaxed

Created a biosensor that stimulates the secretion of sweat when the person is relaxed

Relatively recently, scientists monitor the health of the human body, exploring the composition of its secretions . This led to the creation of a truly advanced biosensors that are able to extract from aqueous solution of salts of...

Augmented reality can now be implanted in the eye

Augmented reality can now be implanted in the eye

While Google thinks what to do next with your glasses Glass and Microsoft is trying to reduce the cost is incredibly expensive AR headset HoloLens, an American eye care company Omega Ophthalmics has developed a very interesting pl...

Discovered a dangerous new strain of anthrax

Discovered a dangerous new strain of anthrax

anthrax is one of the most dangerous diseases can rapidly provoke a large-scale epidemic with a large number of victims. According to the publication EurekAlert, citing the journal Nature, an international team of researchers mana...

To defeat melanoma will help... broccoli

To defeat melanoma will help... broccoli

One of the most dangerous tumors of the human body melanoma, according to various studies, has one of the highest rates of mortality. About 75% of all cases are not amenable to therapy and end with the death of the patient. But, a...

At Harvard have created a material that can seal any wound

At Harvard have created a material that can seal any wound

Undoubtedly, one of the major problems faced by surgeons when conducting emergency operations (or in the case of unforeseen complications) is to combat bleeding. The "standard" methods of coagulation and wound closure is not alway...

#video | Miniature robot implanted into the human body

#video | Miniature robot implanted into the human body

the Idea of creating microbots that "lived" in the human body and monitor the state of health, every year seems less and less fantastic. Because there are a lot of ready-made prototypes, some of which have successfully passed the ...

In Finland created a vaccine against diabetes

In Finland created a vaccine against diabetes

In the world, unfortunately, still plenty of diseases that are not treatable. Patients are forced to take drugs for maintenance therapy to preserve their lives and health. The only hope is to develop new methods of disease control...

The first bilateral transplant of the hands of a child found to be successful

The first bilateral transplant of the hands of a child found to be successful

At the age of 8 years, the American Zion Harvey became the first person on the planet who received a pair of donor resulting from the complex transplant operation. Two years later the doctor, leading his business, spoke about the ...

The first Russian patient implanted with cyberattacks began to see

The first Russian patient implanted with cyberattacks began to see

About three weeks ago, Russia held the country's first implantation in a patient's eye . Bionic eye Argus II, created in 2011, the American specialists, the first established Russian surgeons for four hours. It is now known that t...

Presents operating, located on Board the aircraft, which has no analogues in the world

Presents operating, located on Board the aircraft, which has no analogues in the world

Mobile operating that can be delivered to the most remote corners of the planet, you can save hundreds of lives. Recently, the domestic holding "Schwabe" in the framework of the INNOPROM-2017 project was demonstrated unique mobile...

Encephalon: this musical instrument you just have not seen!

Encephalon: this musical instrument you just have not seen!

in order to create the ringtone, there are a few «checked» tools: you can play it on any musical instrument manually, perform a Cappella or generate on the computer. But there is another way, which offer scientists from ...

Scientists first recorded in the DNA cartoon

Scientists first recorded in the DNA cartoon

we All know that DNA is the carrier of genetic information. But can this structure to store information not only about our genome, but also any other? Numerous studies and experiments showed that it is indeed possible. And recentl...

Medicine of the future: self-managed mobile clinic with artificial intelligence

Medicine of the future: self-managed mobile clinic with artificial intelligence

High technology are designed to make our lives easier, better and safer. Do not stay aside and development in the field of medicine. For example, the company Artefact Group has recently demonstrated a very interesting vision of th...

Scientists brought back an extinct virus, restoring his DNA

Scientists brought back an extinct virus, restoring his DNA

I'm Sure many are familiar with the various works in which scientists in a secret laboratory synthesized a deadly virus. So, the procedure of artificial synthesis of viruses has ceased to be something out of science fiction. For e...

In China brought the world's first genetically modified cloned dog

In China brought the world's first genetically modified cloned dog

recent cloning of the realm of science fiction moved into the category of those branches of science which seem to us commonplace. For example, recently that a group of scientists from China managed to clone several pigs. And their...

Google can access the data of the genome of patients. What?

Google can access the data of the genome of patients. What?

Artificial intelligence is already working for the benefit of health in England, DeepMind because Google provides technologies that help to monitor patients. And here it turned out that Google was found with Genomic England — a co...

Successfully tested a vaccine against cancer

Successfully tested a vaccine against cancer

not the first day, experts from around the world looking for a cure for cancer. And most recently, as reported by the journal Nature, a team of scientists from United States have successfully completed the clinical tests of indivi...