Birth year can affect susceptibility to infectious diseases
Source:
every year the influenza virus kills about 300-600 thousand people
Most Likely, you already know about what causes aging and deterioration of vision, and can increase the risk of cardiovascular disease and brain. Now scientists suggest that year of birth can significantly influence vulnerability for different subtypes of influenza virus. The main provision hypothesis is antigenic “footprint” in the human immune system that appears after a viral disease and remains there until the end of his life. To confirm this theory a group of scientists conducted several studies that were based on seasonal flu activity.
Dangerous influenza virus?
Modern science known 4 genera of influenza virus: A, B, C and D, each of which makes fish, birds, various mammals and humans. However, the influenza virus of type A are able to cause seasonal epidemics and, rarely, pandemics. Scientists attribute this to the fact that the virus has a fast variation, which leads to approximately 198 variants of the subtypes.
During the next seasonal flares of type A, the researchers conducted the new study, which was based on the concept of the phenomenon of antigenic imprinting. The idea is based on the possibility of “fingerprint” or “footprint” on the human immune system after mi in early childhood infectious diseases. Thus, the flu virus can have an impact on the reaction to the end of human life.
It Often happens that two specific subtypes of influenza A virus that cause cough, headache, and fever in humans, normally circulate in nature to each other, from season to season. But since the flu season in 2018 and 2019, was atypical in relation to previous and both subtypes of the virus — H1N1 and H3N2 — circulate in a single season, the researchers decided to take advantage of the situation and studied their impact on people of different ages.
the flu Virus can cause serious complications in people who are at risk
According to an article published on the website , for a detailed study of the phenomenon of antigenic imprinting, scientists needed to collect statistics for the previous seasons the active spread of influenza. Experts managed to identify a definite correlation between age and a specific subtype , which was active in the certain period of time.
As is known, the available 198 variants of the virus of type A can occur in different periods of time, and the two of them — H1N1 and H3N2 — considered to be the most active currently. Based on the available data about the common strains of flu, scientists were able to identify the relationship between year of birth and its vulnerability to an active virus, as is likely, the immune system of some people may associate with certain flu for the first time.
Considering the results of the study, officials in the field of healthcare can obtain the unique possibility to efficiently prepare for the seasonal epidemics of the influenza virus, identifying the demographic groups of people who are most at risk for complications and taking the necessary measures to curb the growth of the disease.
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