A new species of cells that could save thousands of lives. And it's not stem cells
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It would Seem that after so many years of thorough study of human anatomy and physiology, in our bodies should not remain anything that would not fall on the eyes of scientists-physicians. However, researchers are constantly . For example, not so long ago a group of scientists from king's College London found in the liver of a new type of cell that has properties of stem cells, while not being with them.
How I discovered a new type of cells
Recently identified a new type of hybrid is called hepatobiliary hepatic precursors (HHyP). Their existence was known before. They are, as a rule, are formed during early fetal development, but until then it was believed that all these cells the time of maturation and puberty, changing in the liver cells, forming the body. However, it turned out that it is not. , HHyP is stored in small amounts in adults, and they are able to differentiate into hepatocytes and cholangiocytes (two main types of human liver cells).
This is interesting:
The Cells found by single-celled RNA-sequencing. Speaking in plain language, the definition of the sequence of a chain of RNA. At a certain stage of study of liver cells, scientists realized that the data obtained in some cases did not correspond to RNA of normal liver cells. Continuing the study, it became clear that the information obtained was characteristic of HHyP-cells which can behave as stem cells, but they're not.
We first found that in adult liver, there may be cells, similar in its properties to stem — said the study's lead author Tamir Rashid.
Today the only way to treat severe diseases of the liver is a transplant, which, firstly, is not available to all patients and secondly, can lead to serious complications. Opening HHyP opens fundamentally .
What next?
Now a team of scientists is only the beginning of his way, and plans to develop a new methodology for «growing» liver in the near future. In addition, a promising direction is also considered «reprogramming» cells to give them the desired properties. Thus it will be possible to create HHyP in the right amount for each patient.
Moreover, the presence of HHyP in the liver may indirectly speak about the fact that such cells exist in other organs. And if so, in the future doctors will be able
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