As a new microbots will help in the treatment of cancer
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In our portal we have and tiny robots that can act like "the doctors inside," patrolling our body, seeking out and destroying everything that may harm us. While an extremely promising area of application of such microbots — it is a cancer treatment, because even a single lost cell can cause a relapse. And recently, these bots developed by scientists from the California Institute of technology.
the look
By Themselves, the robots have a pretty simple structure. They represent a kind of a capsule in the form of a "layer cake" of the micromotor and of the active substance.
When the capsule reaches the tumor, we can activate it, break the capsule to release the micromotor, and they will move around the area of the tumor. This movement is very important for delivery of drugs — says Wei Gao from the California Institute of technology.
The capsule is Arranged in the following way: its composition is magnesium particles is about 20 micrometers in diameter. First, the layer of gold covers the magnesium, and then a layer of hydrogel containing the drugs to fight tumors that wraps everything else. On top of the capsule is covered with a layer of gelatinous vschestva. Gold and magnesium just act as micromotors. About how they work we will talk later, but for now let us turn to that carried out by American scientists.
but Microbot in the form of capsules. The hole from the bottom — beginning of process of destruction of the shell
Microbots and cancer
A Team of experts fed the capsules to the mice, which in the colon were implanted with melanoma cells to mimic colon cancer. Melanoma were used because these cells absorb near infrared light, so the team can better track the effects of capsules with photoacoustic tomography, which sends infrared light into tissue where it is converted to sound and returns to the image similar to an ultrasound.
This is interesting:
When the capsules reached the colon, the team sent a strong beam of infrared light on them. It heated the gold and due to the temperature difference between the heating of the gold and magnesium, these 2 metal, reacting, act as small motors. Due to the different density and the already mentioned temperature difference, the oscillation of the particles of metala creates a kind of turbulence. Fluctuations in gold and magnesium resemble the work of propellers (like the boat) that makes microbot to advance deep into the tumor, simultaneously .
The Use of drugs in the gastrointestinal tract is a complex task, because they can pass through the intestines further before going to work. We need something that would ensure the long-term effect. The microbots moved around the tumor, so they can penetrate into the tumor tissue and slowly release the drug for a long time” — said Gao.
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