Biomaterial based on hybrid protein will effectively help to heal the wounds
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The Regenerative capacity of our body are quite large and many injuries, healing occurs with virtually no damage, as new fabrics or indistinguishable from the old, or fairly well compensated for their function. However, the ability to heal itself is not infinite, so Arsenal need to have a means to aid the body. A new word in the healing of wounds may be healing a new hybrid protein.
According to the publication Nature Materials, previously it was thought that proteins could exist only in the form of strictly ordered structures in order to perform its function. But in recent years, scientists are actively studying so-called internally disordered proteins. They can take very different forms and still maintain the ability to perform a required function. One of these proteins in the body is elastin — a structural element that provides elasticity to various tissues. It experts and have created a new protein combining areas with ordered and disordered structure.
The study is a group of scientists from Duke University and Washington University in St. Louis. The uniqueness of the material lies in the fact that while being "outside the body" it's a liquid, but once inside it hardens, forming not only a protective layer but also helping regeneration, creating a frame for the sprouting of blood vessels and other cellular structures.
"We were curious to observe what types of materials we could create by experimenting with the composition of disordered proteins." — said Stephen Roberts, one of the authors of the article.
For the synthesis of artificial protein used latinophones polypeptides that can change its state depending on the surrounding conditions. Adding an ordered protein fragments, the researchers were able to create hybrid compounds that have the structural stability of ordered proteins, but is able to pass from liquid to solid.
"This material is very stable after injection. It does not break and it is very well keeps its shape, which is unusual for a material on the basis of protein. Inside the material is easily colonized cells, and the formation of new living tissue, to heal even serious damage."
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