Experimental treatment may help several times faster to mend broken bones
Source:Many of you may know in your experience how long and frustrating it might seem, the process of bone healing, broken in a fall or a strong blow. Fortunately for sportsmen, rescuers and other representatives of the professions whose weekdays are associated with increased risk of trauma, a new study published in the portal , have shown that the combination of only two drugs, can accelerate the release of stem cells from the bone marrow, thereby increasing the rate of restoration of integrity of bone tissue several times.
How to cure a fracture?
Our body — unique mechanism, capable of regeneration. Sarah Rankin, the author of the study aimed searching for the speedy healing of fractures, believes that the main tool that helps in restoring damaged limbs, are our that are activated in the moment when it becomes particularly necessary to ensure the integrity of the living being. However, although our body is strong, even he has limits that are forcing scientists to look for new and better methods of support.
A Significant number of modern medical research is focused on the so-called mesenchymal stem cells, which are a special type of stem cells that can turn into muscle, fat, or even bone. It is known that many modern methods of treatment of various diseases in the development process include the extraction of a small number of stem cells from the body for their subsequent cultivation in the laboratory, then injecting them back to the patient.
A New study aimed at studying the effects of known drugs on the market today, showed that the number of modern medicines is able to mobilize the body's natural ability to release cells MSCS to accelerate the healing of fractures. The results of the report were first published in the journal Regenerative Medicine, where it was also described the testing of two known drugs in a model of spinal cord injury rodents.
a New experimental treatment may help in the treatment of bone damage
One of the two tested drugs were immune stimulant called Plerixafor used to release from the bone marrow in cancer patients, the second was beta-3 adrenergic agonist that is often used to control the operation of the bladder. The result of the mixing of drugs showed that the mobilization of MSCS cells in the bloodstream significantly accelerates the process of bone formation by enhancing the binding of calcium by injury.
The Researchers believe that the results of their published work can help to identify the best methods to treat not only fractures, but also burns and even heart disease. The basic hypothesis of the experts is that the release of MSK is a natural physiological process, contributing to the overall regeneration of the body after suffering injury. If so, open this feature can help to move medicine to a whole new level of development in the coming years.
Anyway, the researchers, of course, there is still further work to understand the practical application in real life. However, as noted by study co-author Andía Redpath, the ability to easily reassign existing drugs to increase the speed of stem cells is the most simple, cheap and efficient method for the rapid healing of injuries and their consequences in comparison with other, more sophisticated methods of treatment that exist currently.
Invented the drug that can restore damaged bone several times faster than before
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