Pharmaceutical boom: what's wrong with antivirals?

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2020-02-21 00:40:18

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Pharmaceutical boom: what's wrong with antivirals? Source:

A Queue in the pharmacies in the autumn-winter period today do not surprise anyone: the epidemic of influenza and SARS annually are profitable to the manufacturers of antiviral drugs. But help do common drugs really are? The producers of “Arbidol” and “Kagotsel” claim that their products have a pronounced immunostimulating effect, remove the symptoms of colds and may even replace a flu shot. Moreover, doctors themselves prescribe antiviral tablets patients. And all anything, if not one “but” — the effectiveness of antiviral drugs has not been proven.

the consequences of irrational thinking

Superstitious , like many cognitive errors of human nature. For millennia, our ancestors built a causal link between different events to learn more about the world and how it works. As we know today, many of their assumptions were false. So, thanks to Nicolaus Copernicus, Giordano Bruno and Galileo Galilee, we learned that the Earth revolves around the Sun. But at what cost? The idea of the heliocentric system of the world the Inquisition persecuted Copernicus, threatening violence. The prosecution was not fatal, but no less tragic. His published writings remained banned until 1848.

The Followers of Copernicus were also persecuted. Not adopted by the Church and academics the ideas of Giordano Bruno on the infinite Universe and plurality of worlds similar to Earth, brought him to the Inquisition: after long years in prison, for failing to renounce his beliefs, Bruno was condemned as a heretic and burned at the stake. In 1633, the process took place over an Italian physicist, astronomer, and mathematician Galileo Galilei, which lasted only two months. Scientist suspected in the support of heretical ideas of Copernicus. The result is a 70-year old Galileo was sentenced to life imprisonment, but was soon placed under house arrest. The detention regime was no different from a prison, and some researchers believe that it was torture.

A Few centuries later, in 1846, Ignaz Semmelweis was was hired as the assistant to Dr. Klein in the Vienna General hospital. In those years in the hospital were just two of the maternity ward, but the difference between them was enormous — in one hospital, the mortality rate of mothers and infants reached 4% and the other 20% and above. If none of the hospital staff could not understand why: in both hospitals, the methods and the conditions did not differ from each other. A year later, a friend of Semmelweis, Dr. Jacob Kolleck, died due to accidental cut with a scalpel during the autopsy in the morgue. Semmelweis noticed that Collecta observed the same symptoms as that of women.

It was then that he suggested that the mortality of mothers and children was because the doctors were transferring invisible “cadaverous particles” on their hands (after the autopsy in the morgue). Semmelweis suggested that doctors wash hands with chlorine solution. The result has not kept itself waiting long: the mortality rate in both hospitals declined to 1-2%. But since in those years science was not yet aware of the existence of Semmelweis had undergone the persecution of the academic community and left for Vienna. In 1861 he wrote a book in support of his theory, and five years later, English surgeon Joseph Lister finally proved the existence of pathogenic microorganisms. However, at this point, the doctor who taught Europe to wash their hands, had died.

About how to properly wash hands, read our

As for us, we were incredibly lucky — we live in the era of technological development, scientific discoveries and breakthroughs in medicine. For the most part, the modern world — it is a world in which the triumph of the scientific method. The constant doubt, test a variety of hypotheses and theories, the recognition of mistakes has allowed us to launch a rocket into space and to eradicate smallpox. What's more, science proves your victory right now, because you are reading this article from your computer screen or smartphone. But it seems at first glance. The lack of information, lack of skills and inability to admit mistakes even in the modern world — the cause of dangerous ignorance and obscurantism.

Why bigotry is dangerous for life?

Despite the widely held view that education in the Soviet Union — the best in the world in the late Soviet Union has been a real boom of pseudoscience. Part of the reason mass obsession citizens clairvoyants and healers is that the schools and universities of the Soviet Union, any incorrect answer is negatively perceived by teachers. Openly Express their opinion on any issues was also not accepted. This means that people have made a habit no doubt in the opinion of the authority, whatever it was. Unfortunately, today the situation has not changed much.

As a result, fear of mistakes, the habit of defending their own beliefs and the ability to build about causation has played with us a cruel joke. People who deliberately refuse vaccination, HIV denialists, supporters of doctors, cancer patients who are treated with homeopathy, often endangering not only his life but the lives of others. And not only in Russia: a good example is the epidemic of coronavirus in China. Wuhan City,the epicenter of the outbreak of a deadly disease, is the center of Chinese medicine in China. Failure to comply with elementary rules of hygiene, distrust of evidence-based medicine, the treatment of serious diseases with acupuncture and drugs from wild animals — all of these factors contributed to the spread COVID-2019. In turn, distrust of the methods of evidence-based medicine annually becomes the reason of premature death of a large number of people worldwide.

In our country today, public health is in decline. This is facilitated by many factors, including low salaries of health workers, shortages of drugs and equipment in hospitals and clinics, etc. Turn to the doctor, long waiting for free ticket for a specialist often leads to the fact that in search of assistance people turn to alternative medicine. When the patient finally manage to get an appointment, it often happens that a doctor prescribes .

Ask your doctor why he recommends to take drugs with unproven efficacy.

It is not Surprising that this state of Affairs drew the attention of scientists. The craze of Russians alternative medicine and homeopathic drugs — the effectiveness of which is not proved — led to the creation of “the false scientific character of homeopathy,” of the Commission of Sciences to combat pseudoscience and falsification of scientific research.

The Memorandum was published on 6 February 2017. According to expert opinion, “ based on their means and methods of diagnosis and treatment are contrary to the principles of evidence-based (science-based) medicine, based on the achievements of the natural and medical Sciences: chemistry, physics, biology, and physiology and topics such as biochemistry, Biophysics, immunology, molecular biology, pathological physiology and pharmacology. Homeopathic methods of diagnosis and treatment of pseudo-scientific and don't work”. The researchers also remind you that homeopathy originated in an era when representations of chemistry and biology about the properties of molecules and the existence of microbes had not been accepted. For this reason in 1847 Ignaz Semmelweis was subjected to harassment.

Homeopathy is based on two laws of sympathetic magic: like cures like. In homeopathic medicines use highly diluted active substance that supposedly causes in healthy people symptoms similar to the symptoms of the patient. Among homeopaths the common belief in the “memory of water”, and that the more diluted a substance, the greater the efficiency has a cure.

The world health organization (who) from the use of homeopathic remedies as treatment of infectious and other serious diseases, and carried out earlier have shown the danger of homeopathy. Also today aware of the fact that the statements of homeopaths on the treatment of cancer, asthma and Ebola turned out to be fake. Highly respected all over the world the Australian national Council on health and medical research conducted a thorough and . As writes the edition , the report confirmed that homeopathy — it is not that other, as the placebo treatment. However, statements by Russian and Australian scientists that homeopathy is not effective for treating any disease caused rapid discontent of supporters of homeopathy. And the Russian pharmacies and is reported unprecedented homeopathic medicines after the publication of the Memorandum No. 2. Nothing like?

homeopathic drugs are still covered by demand.

Yet some deserve censure pharmacists, doctors and those people who promote homeopathy. To pretend that homeopathic medicines are effective and sell/write them to the unsuspecting public at least unethical.

know your Enemy in the face

The Situation is that the audience, without succumbing to the scientific evidence, continues his long and intense love . Worldwide sales of homeopathic drugs number in the millions, and consumers are convinced that these sugar pills help from all ailments. While few people are interested in the real causes of recovery. Homeopaths continue to argue that their approach is based on solid evidence; some even quote “studies” that confirm their point of view. Therefore, before you purchase drugs, you should carefully study their composition. Some homeopathic medicines may not be safe for health substance.

Experts regularly recall that for the treatment of influenza and SARS there are not specific drugs. The fact is that antiviral drugs cannot destroy the virus. To date, the most reliable antiviral medications invented from HIV and hepatitis, not viruses which cause colds andflu. By the way, there are more than 300 and this despite the fact that new strains are constantly appearing. Cold, irrespective of, you take medication or not, is within approximately 7 days.

the Use of homeopathy — the cause of death of large numbers of people around the world.

Below are the most popular antiviral , with unproven efficacy.

the

but

The“standard” antiviral drugs which is sold and produced with the 80-ies of the last century. It is prescribed by doctors with the words “you to take prevention”, often justifying themselves by the fact that the drug is included in the list of required essential drugs (GLNP). At the same time, there are no studies of the effectiveness of “Arbidol”, which would meet the requirements of evidence-based medicine. It is also noteworthy that “Arbidol” is used only in Russia and the former Soviet Union. At the level of world standards evidence base of the drug is absent.

the

Oscillococcinum

At the time of this writing, the cost of the package of Oscillococcinum in pharmacies varies from 432 rubles to 1,500 rubles. Buying “cheap” consumers hope that it will be effective against lung and flu. However, the drug makes you wonder, because the active ingredient, as the manufacturer says, is the extract of the liver musk (or Barbaresco) duck (Anas barbariaelium, hepatic et cordis extractum), which does not exist in nature. In addition to the active ingredient in the composition of “baby teeth” are sucrose and lactose.

cream

This cream also got into the list HVNLP. The manufacturer claims that the drug activates antiviral immunity, reduces the incidence of influenza and relieves the symptoms in two days. The manual says that the “Anaferon” includes purified antibodies that are secreted from the blood of rabbits, as well as sweetener and ballast substances (components of plant foods not digested in the human body). In other words, if you take 100 million tablets of “Anaferon”, there is some probability that one of them would be 1 molecule of the incumbent .

the

Kagocel

“We took cellulose is a polymer made of cotton, took some more substance derived from cotton, combined it with the pulp and the polymer obtained. It is called “Kagocel”” — so in the instructions the manufacturer explains the composition of the drug that is supposedly effective in the treatment of colds and herpes. Starting in 2010, “Kagocel” periodically included in the essential drugs list. All English-language articles, which boasts of the manufacturer, are not clinical studies. This — literature reviews devoted to immunomodulators. In addition to a mysterious substance from cotton in the “Kagotsel” gossypol is present — natural polyphenol that is toxic in free form,which is able to inhibit the spermatogenesis. Gossypol has also been studied in clinical trials as a male contraceptive. In General, the safety of the “Kagotsel” raises serious concerns. Outside of Russia the drug is not used.

To other antiviral drugs with unproven efficacy also includes polyoxidonium, Immunomax, the Isoprinosine, Bioparox, Viferon, Tsikloferon, Ercefuryl, engistol, Imudon, etc.

a scene from the British mini-series . The series tells about a group of friends who try to persuade the cancer kid to go through chemo and refuse alternative treatments

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