RNA editing could be the next step in the development of CRISPR

Date:

2018-09-22 01:15:06

Views:

43

Rating:

1Like 0Dislike

Share:

RNA editing could be the next step in the development of CRISPR

Prestigious Scientists from the Salk Institute reported that they managed to create a map of the molecular structure of the enzyme CRISPR, which allows scientists to more accurately manipulate the functions in the cell. Over the past few years, the CRISPR-Cas9 has fascinated the public imagination for its ability to edit the genetic code with the correction of defects in individual cells — that allows us to treat mutations and prevent the development of many diseases.

Enzymes Саѕ9, in particular, are something of a pair of scissors, cut pieces of the genetic code and inserting in their place the replacement. But these enzymes target DNA which is a fundamental building block in the development of the body, and fears are growing that the use of the enzyme for reprogramming the DNA of a cell can bring more harm than good.

the

NETHERLANDS: harm or benefit?

New data the Salk Institute, published in the journal Cell, provide a detailed molecular structure of the enzyme CRISPR-Cas13d that can target RNA instead of DNA.

Once the RNA was considered as just a mechanism of delivery of instructions, encoded in DNA, for cellular operations, but now we know that it serves biochemical reactions like enzymes and operates its own management functions in cells. Identifying an enzyme that can focus on the control mechanisms of cells, and not on the General plan of cellular function, scientists will be able to perform more precise interventions with less risk.

Simply put, the editing tools can allow scientists to modify gene activity without making permanent — and possibly dangerous — changes in the gene.

Good news, isn't it? Tell us in our

Recommended

Biomaterial based on hybrid protein will effectively help to heal the wounds

Biomaterial based on hybrid protein will effectively help to heal the wounds

the Regenerative capacity of our body are quite large and many injuries, healing occurs with virtually no damage, as new fabrics or indistinguishable from the old, or fairly well compensated for their function. However, the ability to heal itself is ...

Developed a tool for immunotherapy of neurodegenerative diseases

Developed a tool for immunotherapy of neurodegenerative diseases

it has long been known that the cause of the development of many neurodegenerative processes of the brain (including Alzheimer's disease) is the accumulation of amyloid protein that causes the formation of so called amyloid plaques and cognitive func...

Ferromagnetic floating robots — a new word in the diagnosis and treatment of diseases

Ferromagnetic floating robots — a new word in the diagnosis and treatment of diseases

Microscopic robots, which can move inside our body has long ceased to be fascinating and, most likely, sooner or later will find its application in medicine. But more interesting remains: all existing at the moment the robots are based on a variety o...

Comments (0)

This article has no comment, be the first!

Add comment

Related News

In the laboratory for the first time grown tissue of the oesophagus

In the laboratory for the first time grown tissue of the oesophagus

Despite the relatively high ability of our body to regenerate, with some damage to handle, we still are not able to. Therefore, the development of such areas as regenerative medicine, is extremely important. And recently a group o...

Possible eternal life with eternal youth?

Possible eternal life with eternal youth?

Long life seems attractive, but as you age, we become carriers of entire bouquets of diseases and burdens the later stages of life, which prevent us to enjoy our old age. Science is trying to create ways of extending healthy life ...

Genetics re-counted human genes and were surprised

Genetics re-counted human genes and were surprised

the Decoding of the human genome was produced quite some time, but the number of genes was not known exactly. And recently, scientists decided to find out how many genes our genome contains. And the result of the extremely surpris...