With the editor of the genome has been achieved immunity to poison
Source:
Editor genome CRISPR/Cas9 can do this!
Notorious to all readers of our website editor genome CRISPR/Cas9, which allows scientists to make again struck the global community, on what is capable. If earlier CRISPR/Cas9 allowed to change the structure of cells or help to treat a number of diseases, now scientists have been able to give a living organism almost sverhsposobnostyami. Namely, immune to the strongest poison.
As the editor of the genome allows to deal with the effects of the poison?
According to the editors of the magazine , with the help of CRISPR/Cas9, scientists have reproduced in the genome of the fly Drosophila mutations that give immunity to poison ouabaine. Ouabain — the toxin contained in the leaves and stems of the plant Asclepias curassavica (another name — asclepias), which is toxic to most insects, and even humans. Plant cells of the milkweed contain a number of substances which, without going into physiological details, lead to over-stimulation of cardiomyocytes, ventricular fibrillation, and as a result, death from cardiac arrest.
However, a number of insects (e.g., some species of butterflies) have learned to protect their lives due to the fact that they live on branches and leaves of such plants. As you know, these insects have immunity to the strongest poison, and the scientists decided to try «migrate» this property from one insect to another. How do you feel about such frequent use of genome editor? Tell us about it in our
The joint team of scientists from France, Germany and the USA tried «to reproduce the evolution» editor of the genome of CRISPR/Cas9. Took the monarch butterfly, which are immune to the strong poison of the milkweed. It is known that during the development of the species of butterflies at a certain stage, got immunity to poison. Responsible for these processes genes have been carefully studied, and then came . The object of the study, the researchers chose the fruit fly, and with the editor of the genome has created a genetically edited fruit flies with different mutations responsible for the presence of immunity to poison. The number of mutati ranged from one to 5-6 depending on what enzymes are required or not required to develop. All the species of flies were tested for survival in an environment with a high concentration of the poison ouabain.
the Survival rate of larvae (left) and adult Drosophila (right)
In the end, scientists found that three separate mutations in the enzyme system, it is sufficient to have resistance to poison. Scientists note that their experiment will help in the development of new methods to combat poisons and toxins, as well as in the creation of drugs that can act at the gene level. However, the uniqueness of the work not just that. What did the team of experts from the three countries — that has helped not just «add» to a living organism a new property, but also allowed us to reproduce a multi-step process of adaptation at the example of how it was in the process of evolution.
Recommended
What will be the shelter for the first Martian colonists?
Mars is not the friendliest planet for humans While the Red Planet is roaming rovers, researchers are pondering the construction of shelters and materials needed by future Martian colonists. The authors of the new paper suggest that we could use one ...
New proof of string theory discovered
Just a few years ago, it seemed that string theory was the new theory of everything. But today the string universe raises more questions than answers String theory is designed to combine all our knowledge of the Universe and explain it. When she appe...
What is the four-dimensional space?
Modeling camera motion in four-dimensional space. View the world in different dimensions changes the way we perceive everything around, including time and space. Think about the difference between two dimensions and three dimensions is easy, but what...
Related News
What is the Malthusian trap? And where does the Avengers?
In a beautiful modern cities to live comfortably, but not always pleasant. Modern society is often called consumer society. Don't forget that we consume in the first place, not the new iPhones, and other benefits of technology dev...
How to increase your productivity
Fashion trend on self-development has distorted the very idea of development. often think of social approval, not about how to increase productivity. Personal development training, motivational books and webinars — the more the be...
What is the doomsday clock? Little-known facts and opinions
Colorful scenario of destruction of everything on earth More than sure that many of you have heard of the doomsday clock — the ominous name of some obscure hours, which is constantly being transferred closer to midnight. Act...
The Fibonacci Number. Why it is so popular in nature?
"the Vitruvian man" by Leonardo da Vinci has the ideal proportions, based on knowledge of the properties of Fibonacci numbers the Mysterious Fibonacci number equal to 1,618, excites the minds of scientists for several millennia. S...
Discovered DNA of the parasite, who lived 17,000 years ago
One of the types of roundworms. Fairly common parasites of man and animals As is known, the parasites co-existed with us and other members of the animal world throughout our life cycle almost since the origin of life. Thus despite...
How social networks help to spread pseudoscience
Let's be Frank — spirit in 2019 is a little different from the 1990-ies of the last century. This is not about politics and Economics, though, of course, interrelated. Today, as 30 years ago, in Russia there is the era . And if th...
In the Netherlands opened the world's first "floating" farm
We have already wrote many times about , but perhaps we have never touched upon the subject of the floating farms. Imagine they exist! In addition, one of such places is located in the heart of Western Europe — in the Nether...
Each of us knows from experience that if you make at least a small yawn even in the smallest team, then you can start a whole chain of this strange but amusing phenomenon. Moreover, some people simply think about this soothing pro...
Why are conspiracy theories so popular?
When was the last time you accessed the Internet, did not notice anything strange? There is at least a little to pay attention to the comments under the popular blogs, how to catch the eye of conspiracy theories of all stripes. Pe...
Cockroach milk — food for the future?
due to the fact that the population of our planet is constantly growing, scientists now are finding new ways to feed . So, one of the most promising products of the future may well be cockroach milk. Despite the fact that currentl...
How does artificial intelligence
In recent years we . It is used almost everywhere: from the sphere of high technology and complicated mathematics to medicine, automotive industry and even with smartphones. The technology underlying the work of AI in the modern v...
If you think that such diseases as measles, tetanus and whooping cough are no longer a threat, we have bad news for you. In the last few years around the world is gaining popularity the movement of the opponents of vaccination. In...
What will happen to the snake if it gets bitten by another snake?
I Think that it is not necessary to explain what can happen to humans by the bite of a poisonous snake, because of the unpleasant consequences of such events many people have heard. But what happens if a snake bites another snake?...
Scientists have proposed a new method for the production of renewable energy
According to scientists from Stanford University, where blended salty ocean water with fresh water, can be a source of huge production volume , according to a press release on the University website. The authors note that this tec...
Why after the mint we feel cold in your mouth?
If you chew on a mint leaf, you will feel how your mouth begins to spread a pleasant coolness. This is due to the substance menthol, which is contained in mint and affects the system of receptors that are found on the mucous membr...
The first ever picture of quantum entanglement
Physicists from the Scottish University of Glasgow reported an experiment in which scientists were able to get the first ever photograph of the particles. Phenomena by the standards of physics are so strange that even the great sc...
The biggest rat in the world was the size of a dog. They ate people
the Giant rats, which are ten times the size of their modern relatives, were found on the island some 1000 years ago. To such conclusion have come the archaeologists after the discovery of the remains of the seven giant rodents. A...
As Fukushima has become a second Chernobyl
on 11 March 2011 at Fukushima-1, located in the homonymous Japanese city, in a strong earthquake and tsunami, which claimed approximately 16 million lives, there was a major radiation accident. A natural disaster brought down not ...
Nikola Tesla: the most amazing inventions of the great genius
Exactly 163 years ago this day was born Nikola Tesla. Hardly on this planet there are people who have not heard about it. The name of Nikola Tesla called the company, he was considered great, his secrets, trying to unravel today. ...
What happens if you melt the biggest glacier in Antarctica?
for anybody not a secret that most of the ice on our planet are concentrated on the South and North poles in the "upper" and "lower" caps of the Earth. In other regions, just too warm for the existence of "permafrost". Can you ima...
Comments (0)
This article has no comment, be the first!