Found a way to use the immune system for tissue regeneration

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2019-11-20 22:20:09

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Found a way to use the immune system for tissue regeneration Source:

Immune system will help in the regeneration process

The Human body never ceases to amaze. Although it would seem, on our level of technology we have long since had to learn everything about him. However , a group of researchers from the University of Bristol (UK) has discovered a way to manipulate its own immune response of the body to stimulate .

The Results published reveal information about a new network of factors for protecting cells from damage. This discovery may greatly help patients undergoing surgery or trauma, speeding recovery time and reducing the risk of complications.

How the immune system AIDS in tissue regeneration

When the tissue is damaged as a result of injury (or during surgery), the body quickly «recruits» immune cells to the site of injury, where they destroy infectious agents, which in any case will appear in this place. In addition to absorbing the alien infectious agent, the immune cells produce a number of potent molecules for fighting infection. For example, a number of substances contain forms of oxygen known as «active oxygen» — something like peroxide.

However, these antibacterial products are also very toxic for the host tissue and can disrupt tissue. To counteract these harmful effects, recovering the fabric activates potent protective mechanisms. Researchers from Bristol University have identified how to stimulate this process in normal undamaged tissues.

In healthy people, tissue damage is usually quickly restored after damage. In healing the wound of the skin activates the stress response, which uses immune cells to eliminate invading pathogens. — says Dr. Helen Withers, lead author of the work. In this study, we closely watched how the restoration of wounds, and watched the behavior of immune cells. However, we found a network of protective pathways that protect tissues from inflammatory damage and make them more «sustainable». We also demonstrated that the individual activation of these pathways further enhances the protection of tissues, in that time, as their containment led to a significantly worse regeneration process.

The results Obtained are of great importance for patients, as the therapeutic activation of these pathways may allow the development of approaches for early activation of the immune system of the patient before surgery. That will improve not only the course of the operating process, but also reduce the percentage of complications. If you are interested in this topic — be sure to follow us on.

Currently, scientists are exploring the possibility of activation and other paths «sustainability», which help protect tissues from injury in the points of injury and damage to other organs not associated with injuries. For example, the tissue toxins and waste products of pathogenic microorganisms. Scientists realized that all the protection mechanisms are activated by the same pathways, the inflammatory reaction described above. Therefore, the researchers believe that the immune system can more accurately «reconfigure» on reconstruction and regeneration of tissues and organs.

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