Genes that begin to work after death

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2020-03-14 11:20:10

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It May seem that we know what . At least, I think so. But the simple definition of death, cardiac functioning of the body – does not take into account how really strange our bodies are. As told to Peter noble, former Professor at the University of Alabama, scientists do know practically nothing about what happens when a person dies. Noble knows firsthand that the one who studies death, waiting for surprises: for example, he helped that dormant genes can be activated in a few hours or even days after death. But how and why this happens?

Creepy zombie genes

A Gene is a set of chemical instructions made up of DNA that tells the body how to do something. When activated, these chemical instructions are transcribed to RNA, and the cells can then use the copied sequence as a framework to build complex molecules. If you imagine that a gene is a recipe in a cookbook, activation is a list of cooking ingredients.

In the study, noble and his colleagues from the University of Washington tested the method of measuring the activity of genes. As a control were analyzed tissues of the recently deceased Zebra. The researchers expected to see a steady decline of the genes by decreasing cellular activity. However I found something amazing – with a few notable exceptions. After the Zebra had died, about one percent of their genes alive. It looked as if the cell were preparing to build something.

Some genes that are activated after death, are associated with cancer development.

The Idea that genes are activated after the death of the body is incredible, so the researchers decided that the reason for the obtained results is the fault of the equipment. But repeated tests conducted on the fish and then mice, continued to confirm the impossible: genes are activated through the or even days after the death of the body. The scientists ' conclusions were met with skepticism until a group of researchers under the direction of roderich Guigo of the Barcelona Center for genomic regulation is also not a post-mortem activity of genes, this time in humans. Guigo and his team studied the regulation of genes by analyzing tissue of people who donated their bodies after death. Their work was already in full swing when the article was published noble, so they were not surprised by the results of his team.

What genes are activated after death?

In the future the obtained results can give scientists a better understanding of how genes work in living organisms and how the bodies are changing at the molecular level after death. In progress the researchers also found that different genes are activated in different time intervals after death – one of them can regularly be activated in six hours after death, while the other can be activated after 24 hours. Forensic experts could use this information for a more accurate estimate of time of death.

the Death of one of the greatest mysteries of mankind

Despite the opportunities offered by the research results, the reason why genes are activated after death is unknown. Scientists do not exclude that the clue may lie in the types of these genes. Although none of the zombie gene, apparently, does not lead to physical changes after death, many of them are connected with activities which usually strictly regulated or suppressed by the body. They are responsible for the beginning of the formation of the spine – if you have it there, so new is not needed. Other genes that are activated after death, are associated with cancer development. In General, the results of these studies have shown that death is a more subtle process than previously thought. Death does not mean that all the billions of body cells instantly stop working. Death means they no longer work together. The hours and days during which these relationships disintegrate and the life fades away, are the new frontiers for science.

Nobody knows what really happens to human body after death

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