Scientists are questioning the existing classification of diabetes mellitus
Source:
Diabetes mellitus is one of the most common and almost incurable diseases today. And as you know, doctors have identified 2 types of this condition. However, according to a recent study conducted by scientists from the Swedish Lund University and Finnish Institute of molecular medicine, a number of varieties of diabetes could rise to 5, which would mean the emergence of new therapies, as well as the fact that some existing treatments are not sufficiently effective.
To begin, let's understand the commonly accepted classification: type 1 diabetes is associated with insufficient production of insulin cells of the pancreas as a result of their destruction (for a variety of reasons). Cause of type II diabetes is the loss of tissue sensitivity to insulin. That is, in 1 case the insulin is produced insufficiently and the second cell of the human body no longer "see" the insulin under normal (or even elevated) concentrations in the blood.
According to a study published in the Lancet Diabetes & Endocrinology, we can distinguish 5 types of the disease. A group of scientists from Sweden and Finland conducted a cluster analysis of the data collected 8980 from people who have recently been diagnosed with diabetes. They evaluated data such as patient age, body mass index, activity of the islets of Langerhans (cells that produce insulin), insulin sensitivity, as well as two clinical marker used in the diagnosis of diabetes: glycerinogenes the concentration of hemoglobin and the presence of antibodies against glutamate-decarboxylase.
As a result, scientists came to the conclusion that among all the patients can distinguish not 2 but 5 types of disease: type 3 is the severe form of 2 – moderate. 1 group is 11-17% of the patients, and they have a high risk of developing renal failure as a complication. 2 heavy group (9-20%) are young patients with insulin insufficiency is autoimmune nature. The third (6-15%) – persons with insulin deficiency autoimmune nature. "Light" form of diabetes associated with age-related changes of the pancreas (approximately 40% of patients) and obesity (18-23%). Moreover, the scientists repeated the experiment in a group of 5795 people and got similar results.
Thus, the experts came to the conclusion that a proper treatment requires a more careful diagnosis of the type of diabetes because only a portion of patients involved in the study (namely 1,2 and 3 groups) needed insulinsecreting therapy. Moreover, autoimmune type of insulinorezistentnost requires a completely different approach in treatment. The authors of the research do not exclude that during the next stages of the research may change and the data obtained are preliminary, and further experiments can refute them.
Recommended
The coronavirus has mutated into 30 new strains
While coronavirus Apocalypse slowly but inevitably becomes routine, the virus SARS-CoV-2 continues to evolve. And, unfortunately, he was good at it. Writes , with reference to the South China Morning Post reports that new studies show that the virus ...
In the United States recognized that the ventilator dies 88% of patients with coronavirus
When the world is raging coronavirus that causes pneumonia and kills people, the only solution is intensive care. If this is not done, the victims will be very much. Today for severe patients there is only one solution — connected to the appara...
Can a transfusion of blood plasma to cure the coronavirus?
Typically, vaccination involves the introduction into the organism of the weakened or killed microorganisms (viruses) designed to create a strong immunity to possible future infectious diseases — that is, for selection of antibodies. But what i...
Related News
Tools CRISPR mastered three new tricks
CRISPR, gene editing superhero, become a bit more powerful. Last week in Science was published three studies in which leading laboratories from around the world presented the latest additions to this technique, converting editor g...
Scientists understand the "enzyme of immortality"
About the quest for immortality or at least prolong life written not one novel, not one shot film and conducted a lot of scientific works. But the fact is that the so-called immortality enzyme was found already long enough, but to...
Google teaches the neural network to predict the death of a person
Modern medicine aims to prevent and anticipate the development of serious life-threatening diseases. However, forces and human knowledge is often not enough to predict certain complications. To help doctors in the future may come ...
Russian scientists have developed "living" bandages
Despite the fact that the skin is the body having a sufficiently high capacity to regenerate, yet with a serious injury like burns or deep wounds, it can not recover completely. Therefore, in some cases, resort to transplant skin ...
Scientists from USA have developed a synthetic analogue eyes
the New invention presented scientists from the School of engineering and applied Sciences at Harvard University — they have created an artificial eye, working on the principle of human — RIA «news» citing Th...
We often wonder why some no problems in the 9 years experience in programming (like Elon Musk, who gave the computer it was in these years) and others in this time can barely remember the multiplication table. These and many other...
Organs for transplantation will grow... in sheep
without a doubt, one of the most serious diseases are those that so strongly affect the human organs that become unable to perform its function. Then you have to resort to transplantation. However, not every transplanted organ wil...
Scientists find unusual use of the editor CRISPR genome
All people interested in science probably already heard about the editor of the genome of CRISPR. It has repeatedly used for making changes in the genetic code in a number of other similar experiments. However, as will be reported...
Microscopic somersaulting robots will be used in medicine
the Use of microscopic devices and even in medicine it becomes the last time something taken for granted. But engineers do not stop working in this direction and each year submit their new invention makes life easier for doctors a...
In Japan created the perfect remedy for the flu
Japanese pharmacists announced the creation of the drug against the flu that can kill the virus within days. It operates much faster than existing counterparts and requires only a single dose, according to the Washington Post. th...
Scientists first managed to re-create lung tissue
stem cell therapy is increasingly used in medical practice. For example, a group of Chinese researchers from Tongji University not too long ago just found a new use of a known technology, but also made a small breakthrough in medi...
Opened a way to "disable" the resistance of cancer cells to anticancer drugs
One of the main problems in the treatment of cancer is not only a very rapid proliferation of tumors but also their ability to develop resistance to different chemotherapy. This leads to the fact that the treated tumors may come b...
Doctors will use QR codes instead of drugs
Despite rapid development of pharmacology and the emergence of new types of drugs and treatment methods, the main method of delivery of tablets, capsules and pills did not change over the entire history: medications you need to dr...
Smart home not only automatiseret your life, but also help to monitor the health of
it took more than fifty years since the first time we have seen the future of smart homes, represented in the popular animated series "the Jetsons." Rumba, of course, not really like Rosie, but in modern homes the advanced technol...
Canadian scientists have created almost perpetual dental fillings
the majority of the population of our planet has those or other problems with the teeth. And almost all of us have fillings. But seals are short-lived. They are destroyed and require replacement. Recently, however, scientists have...
Scientists have discovered genes of regeneration
As you know, there are on our planet creatures that have an incredible ability to regenerate, allowing you to grow lost limbs and recover the bodies. Many scientists have long argued that virtually any body has the same possibilit...
Created controlled by the power of thought arm exoskeleton
the Swiss engineers from the Federal Polytechnic school of Lausanne have created a working prototype of the exoskeleton of the hand, which can be controlled by thought. The developers were able to dispense with the implantation of...
Canadian scientists have created a synthetic smallpox virus
Despite the fact that many existing viruses not yet defeated finally, there are all the same and the ones that humanity has managed to cope. One of these is the smallpox virus, but a group of researchers from the University of Alb...
Scientists closer to creating universal flu vaccine
the Flu each year reaping his victims. Scientists and doctors save lives, regularly rolling in the seasonal vaccine and deploying medicines to combat the virus and secondary infections. Nevertheless, the flu has killed tens of tho...
Invented a new kind of blood test for cancer diagnosis
Diagnosis of many life-threatening conditions are often hampered by the fact that their definition of required is not always easy to perform manipulation. However, a group of American researchers proposed a method of diagnosis of ...
Comments (0)
This article has no comment, be the first!