Alzheimer's Disease today is the most common form of dementia. According to who forecasts, the total number of people who are likely to develop this disease by 2050 could grow to 100 000 people annually. But, according to a study published in the journal Neurobiology of Aging, Alzheimer's can affect not only humans but also other primates. In particular chimpanzees.
As a rule, the disease develops gradually. After the appearance of first symptoms in humans begin to observed violations of short-term memory and then long-term loss of memory, including memories about the self and about your family. According to modern concepts, the disease develops due to the fact that in the brain begin to form amyloid plaques (insoluble concentrations of specific molecules). A group of American scientists from Ohio state University not long ago found that in the brain of a chimpanzee also can be detected by such education.
Experts have studied the brain 20 monkeys died at the age of 37 years and older. In the brain, 12 of them were discovered amyloid plaques. In addition, researchers have identified structures that precede the formation of neurofibrillary tangles of excessively phosphorylated Tau proteins. The discovery of two of these signs is observed in a person suffering from Alzheimer's disease.
Now scientists aim to experimentally establish whether amyloid plaques on cognitive abilities of monkeys. This will help to better understand the nature of dementia and also to determine whether amyloid plaques and Tau proteins are the root cause of the disease or something else leads to the progression of dementia.
It is also Worth mentioning that at the moment Alzheimer's disease is not responding to therapy, despite the fact that being constantly developing drugs for treatment and clinical trials. For example, a group of scientists managed to synthesize a drug that reversed the development of Alzheimer's disease in rodents, but clinical studies of the drug have not been completed so far.
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