Robot scientist discovered a new drug
Source:Development and testing of new drugs – employment is extremely long and labor-intensive. But, like everything in the modern world, this area of pharmacology is sometimes to "instruct" robots, because they can calculate all possible outcomes and give the most appropriate formula. This approach is particularly important in the field of developing drugs to which the pathogens quickly develop resistance. And here, according to the publication Science Daily, researchers from the University of Cambridge and artificial intelligence could create a new drug against malaria.
Recall that malaria is a very dangerous disease that only in Africa and Southeast Asia, claiming the lives of more than half a million people a year. The problem of prevention and treatment of malaria in the fact that some strains of Plasmodium falciparum (the causative agent of malaria) very quickly develop immunity to the drugs and must constantly seek new "weak points" of this dangerous microorganism.
In order to identify, by means of which you would win of Plasmodium the scientists used a robot scientist called Eve. AI robot the analysis came to the conclusion that the new drug can be a substance triclosan (which, by the way, is very often added to toothpaste to fight bacteria in the mouth). Triclosan inhibits the enzyme was enoyl-reductase, which is involved in the synthesis of fatty acids and nourishment to the cells.
Found out that triclosan could inhibit growth of the culture of one of the stages of Plasmodium falciparum. However, during the experiments, the scientists found that triclosan affects another enzyme of Plasmodium — digidrofolatreduktaza. It had tried to suppress the other anti-malarial drug, pyrimethamine, but in the world there are strains resistant to this drug. So, triclosan was effective against these resistant strains of Plasmodium. Given the relative cheapness of production of triclosan, mass production of a new drug can begin in the near future.
Recommended
What will be the shelter for the first Martian colonists?
Mars is not the friendliest planet for humans While the Red Planet is roaming rovers, researchers are pondering the construction of shelters and materials needed by future Martian colonists. The authors of the new paper suggest that we could use one ...
New proof of string theory discovered
Just a few years ago, it seemed that string theory was the new theory of everything. But today the string universe raises more questions than answers String theory is designed to combine all our knowledge of the Universe and explain it. When she appe...
What is the four-dimensional space?
Modeling camera motion in four-dimensional space. View the world in different dimensions changes the way we perceive everything around, including time and space. Think about the difference between two dimensions and three dimensions is easy, but what...
Related News
Physicists accelerate beams of light in a curved space in the laboratory
Physicists have managed to demonstrate the acceleration of the light rays on flat surfaces when accelerating led to the fact that the rays follow curved trajectories. However, a new experiment has expanded the boundaries of what y...
Scientists have created a gamma ray burst in the laboratory
Gamma ray bursts, the powerful flashes of light — these are the brightest events in our Universe, which do not last longer than a few seconds or minutes. Some are so bright that they can be seen with the naked eye, like burs...
Physics of the Tomsk state University are developing levitation 3D printer
a New method for ultrasonic 3D printing has developed the physics of the Tomsk state University. Recently they have developed a setup for levitation of small particles that will be used as the basis for the levitation of a new 3D ...
Appeared in Dubai's first vertical farm
the world is not the first day is developing projects for the greening of cities and the establishment of so called «vertical farm», which will not only improve the ecological environment, but also significantly save spa...
10 scientific stories of 2017, which will seem fantastic
And now it is time to sit down, look back, take a deep breath and look at the headlines of scientific articles that we might otherwise miss. Scientists are constantly pleasing us with new developments in various fields. Nanotechno...
Six houses of the future which will protect you from climate change
Floods, droughts, hurricanes, forest fires, once rare weather events are becoming more common and powerful because of climate change. And it is impossible to deny. At the same time, more and more people move to cities around the w...
Glowing plants will illuminate the streets
On the streets of our cities we used to see a lot of plants that carry out, as a rule, purely decorative function. But what if all this flora it would be possible to give additional functions? For example, the day plants produce o...
Scientists from MIT created a tattoo from a living cell
Researchers from Massachusetts Institute of technology (MIT) invented a temporary "tattoo" consisting of a genetically engineered living cells. Their prototype is similar to a transparent sticker with a pattern resembling wood. Th...
Russia is working on a wheelchair controlled by gaze
High technology are designed not only to facilitate our lives, but also improve the quality of people with disabilities. Russian scientists on the basis of the research center "Kurchatov Institute" has developed a new wheelchair g...
How to make a trip back in time physically possible?
the Idea that we could go back in time to change the past, became one of the favorite techniques in movies, literature and television series. "Harry Potter", "Back to the future", "Groundhog Day" and many other movies promised us ...
Presented home solar installation for the production of water from air
Despite the fact that at the moment, the question of depletion of drinking water is not raised too often, however, fresh water is gradually ending, so many companies today are engaged in creating solutions for "alternative" extrac...
Russian scientists have developed ekotoplivo from waste
the High content of carbon dioxide in the atmosphere, according to scientists, is the main cause of the greenhouse effect, and the particles of ash may contain heavy metals, toxins and carcinogenic trace elements. Therefore, the q...
10 secrets of science that will make you immortal in this century
With each passing day science brings humanity to the old dream: immortality. The path to immortality is thorny and difficult, but the end goal justifies any means (although this is debatable). It is highly likely that born in this...
CERN again "groped" new physics
From the mid to late twentieth century quantum physics has dismantled piecemeal a unified theory of physics proposed the General theory of relativity. Physics is a great subject to gravity, but only quantum physics can describe ob...
Russian scientists have created an analyzer of ground for the mission "Eczemas"
in the Spring of 2012 the European space Agency and the Russian space Agency has scheduled a joint mission «Eczemas», which consists of 2 stages: launch the Trace Gas Orbiter (TGO) and sending the Rover «Pasteur...
Presented a brain implant that improves memory by 30%
Ways to improve memory at the moment there are many but they all related to the rather monotonous process of training the brain. At the same time after time, attempts are being made to improve the functioning of the brain using el...
Created fabric that is simultaneously warm and cool
Just imagine the clothes that depending on environmental conditions and is able to warm people, a refuge from the cold, and cooled if the weather is very hot. But clothes that are hard to imagine without right , and that is this f...
What if you became... dark matter?
the human Body consists of approximately 1028 particles that are mated together. A normal person weighs 50 to 100 pounds and is on the surface of the Earth. But dark matter behaves differently. She does not interact with the nucle...
That can make science 600 billion dollars?
the U.S. spends on military spending more than all ten of the following countries combined: $ 600 billion a year. It is almost ten times more than it spends on military spending Russia. Meanwhile, the joint budget of NASA and the ...
Can machines have consciousness, according to neuroscientists? It seems that Yes
As if the Director wanted to force you to believe in it, the protagonist of the film "the car" in 2015, directed by Andrew Garland, is not Caleb is a young programmer who has been assigned to assess machine consciousness. No, main...
Comments (0)
This article has no comment, be the first!