Scientists restore memory in Alzheimer's disease
Source:
One of the most unpleasant manifestations of Alzheimer's disease is the gradual loss of memory and memories, which radically changes the whole personality of a person. However, it is possible that soon we will be able to handle it. At least, according to reports, a group of experts from France and India were able in the course of a series of experiments to fully restore in laboratory animals with Alzheimer's long term memory and to restore severed neural connections in the brain.
Responsible For the development of a group of experts from the Department of molecular biology and genetics, Centre for policy research studies. Jawaharlal Nehru (JNCASR), headed by Professor Tapas Kundu. They managed to create a molecule that the brain activates 2 of the enzyme — acetyltransferase of histones, CBP and P300, which are responsible for the formation of neural connections.
"We wondered if the molecule might improve memory in healthy mice, then will she be able to recover lost memory in mice with Alzheimer's disease? We found a molecule that activates two enzymes in patients and mice produce new neurons. In addition, 81 gene, expression of which was suppressed in mice with Alzheimer's disease, was activated to a normal state. In addition to the full restoration of the lost memory, we studied and other symptoms of Alzheimer's disease." — said Professor Kundu in an interview with the Journal of Neuroscience.
Researchers believe that most clinical trials of Alzheimer's disease have failed from the fact that the memory disorder occurs in the later stages, when the brain is already affected with deposits of an abnormal protein and has a damaged neural connection. In the course of work, scientists have found a way to reverse the damage and restore neural connections.
"There is a likelihood that the molecule, at least can delay the development of cognitive dysfunction. In addition, in laboratory animals, we observed no development of signs of progressive brain damage. Currently, we are studying mice with Alzheimer's, which a year. And the first results are encouraging. Long-term memory in animals do not suffer."
This and other news you can discuss in our
Recommended
Can genes create the perfect diet for you?
Diet on genotype can be a way out for many, but it still has a lot of questions Don't know what to do to lose weight? DNA tests promise to help you with this. They will be able to develop the most individual diet, because for this they will use the m...
How many extraterrestrial civilizations can exist nearby?
If aliens exist, why don't we "hear" them? In the 12th episode of Cosmos, which aired on December 14, 1980, co-author and host Carl Sagan introduced viewers to the same equation of astronomer Frank Drake. Using it, he calculated the potential number ...
Why does the most poisonous plant in the world cause severe pain?
The pain caused to humans by the Gimpi-gympie plant can drive him crazy Many people consider Australia a very dangerous place full of poisonous creatures. And this is a perfectly correct idea, because this continent literally wants to kill everyone w...
Related News
An experiment was initiated for modeling the first artificial quantum life
Modern computers give a lot of possibilities for simulation of different situations. However, any calculations will be somewhat "linear", as they are subject to clearly defined algorithms, and can't retreat. And this system does ...
"Quantum vibe" can reveal the secrets of matter
Over the last few years some materials were ground for physicists. These materials are not to be made of something special — ordinary particles, protons, neutrons and electrons. But they are more than just the sum of their parts. ...
China accused of stealing secrets from American technogiant
the Tiny chips that were introduced in the American computer equipment manufactured in China, were used in efforts by Beijing to steal U.S. technology secrets, said in a report published on Thursday. Bloomberg claims that these ch...
Font created to help you remember to read the text
have You ever had several times to re-read the text to understand its essence? This problem is probably familiar to all — as a student, faced each. Researchers from Royal Melbourne University teamed with a local design school and ...
Created material that produces hydrogen fuel through artificial photosynthesis
In the course of evolution and the evolution of species, nature had "invented" a number of very interesting processes, which even at present development of technologies to reproduce is extremely difficult. One such process is pho...
Saturn devouring his own ring. Coming to the planet will soon disappear
Worked around Saturn for almost 20 years, NASA's space probe "Cassini" even in the last moments of his life did not cease to transmit to Earth the amazing facts about the gas giant. After analyzing another portion of the informati...
Discovered microquasar emitting powerful gamma radiation
The study of distant (and not) space can shed light on the structure of our galaxy and even the universe. Every day scientists from around the world are watching celestial bodies and galaxies and very often these works are reward...
The crew of "Soyuz MS-08" returned to Earth unharmed
the Crew of the manned transport spacecraft (WPK) "Soyuz MS-08" safely on the Ground today after undocking from the International space station, according to Roscosmos. The descent module landed in Kazakhstan steppe on 4 October 2...
For the first time revealed the structure of the protein responsible for antibiotic resistance
The formation of bacterial resistance to antibiotics is studied well enough and preparations for combating harmful microorganisms still do not allow them to take over from us. At the same time remained in the mechanisms of develo...
The volunteers played "Tetris" with the power of thoughts
In 2017, the founder of Tesla and SpaceX Elon Musk got the idea to create an interface to directly exchange information between human brain and computer. For this he is , but there is a great probability that in the embodiment of ...
The new study limits the contribution of black holes to dark matter
Statistical analysis of 740 supernova explosions found that the black holes may have no more than 40 percent of the amount of dark matter present in the Universe, which, in turn, scored another nail in the coffin of the theory of ...
The project will examine Breakthrough Listen a million stars for signs of thesignature
to Listen Breakthrough Project aimed at the search for extraterrestrial life, expanding its capabilities with the announcement of the inclusion in the programme of use of a network of radio telescopes MeerKAT, located in the North...
Artificial intelligence DeepMind learned to come up with pictures
a British company DeepMind in 2014 which became part of Google, is constantly working to improve artificial intelligence. In June 2018, her staff presented a neural network, capable on the basis of two-dimensional. In October, the...
Proved negative impact of cosmic radiation on the gastrointestinal tract
Long-term space flights and even just stay in earth orbit is hardly beneficial for health. Zero gravity and cosmic radiation have not the most positive impact on our body, which adds to the difficulties in implementing long-standi...
Who said that dogs have exceptional intelligence?
People who believe that dogs have a unique intelligence, you're barking up the wrong tree, scientists say. They revised the work, which compare brain power of dogs and other Pets social predators and carnivores (this includes dogs...
First discovered dust storms on Titan show its similarity with the Earth
Since then, as the probe Cassini entered the Saturn system in July 2004, scientists and the General public has received a steady stream of data from the ringed giant and its many wonderful companions. In particular, special atten...
Started the most ambitious project of sequencing human DNA
recently on our portal we wrote about the fact that in DNA the number of genes was much more than we previously thought. But the experiments with the carrier of genetic information and do not even think to end. For example, just r...
Non-surgical treatment of appendicitis has shown its effectiveness
the Report of the Finnish scientists on the five-year study of options for the treatment of acute appendicitis with appendectomy (removal of Appendix) and antibiotics, says about the effectiveness of the latter method. The results...
The Japanese space Agency has revealed new images from the surface of the asteroid
the Japanese aerospace exploration Agency (JAXA) has published a new portion of data obtained from the asteroid Rovers, MINERVA-II1, successfully carried out the landing on the asteroid Ryugu 21 September in the framework of the m...
The new mechanism will allow to store information in one atom
Scientists from the University of Radboud discovered a new mechanism for the magnetic storage of information in the smallest unit of matter: an atom. Despite the fact that proof of principle has been demonstrated at very low tempe...
Comments (0)
This article has no comment, be the first!