An experimental "cocktail" of known drugs extended the life of the living organism 2 times
Source:
In the field of anti-aging and creation of new methods of rejuvenation and prolongation of life, provided one is already a lot of experiments. But they are all associated with the development of something new (and therefore expensive and unavailable). However, a group of researchers from Singapore has decided to use for this purpose are already known drugs and one of the resulting combinations is practically doubled the life expectancy of the subjects, the animals involved in the experiment.
It is worth to mention that the experiments were conducted at the round worm, Caenorhabditis Elegans. But despite the fact that on the evolutionary ladder they are located quite far from people, many trials of various drugs and methods very often begin with these worms.
These representatives of the animal world there is enough "common ground" with human genetics and in this case, scientists from the National University of Singapore wanted to find out how the interaction of different chemicals will affect the body (albeit small) in its entirety.
"We wanted to find out whether it is possible to increase life expectancy by influencing the different ways of aging by means of combinations of drugs."
Through a series of different tests scientists have created the most suitable for the tasks a cocktail (but we still recommend to play it at home). It includes the immunosuppressant rapamycin, which is commonly used to prevent rejection reactions of the transplant, the antibiotic rifampicin (used for tuberculosis), Metformin (a drug indicated for diabetes of the 2nd type), allantoin (local antiseptic, which can be found in the composition of various cosmetic products), and psora-4 (selective potassium channel blocker).
the change the lifespan of worms when taking separate drugs
the change the lifespan of worms when taking different combinations of medicines
In the end it turned out that the best combination of all the medicines (proportion for obvious reasons, kept secret) has resulted in longer life 2 times. However, such combination was not harmful or toxic to the worm. But the findings require further analysis and long-term tests on more advanced animals.
"If we can find a way to extend the life and delay the aging of people, we will win not only increase lifespan, but also from getting rid of age-related diseases such as arthritis, cardiovascular disease, cancer or Alzheimer's."
This and other news you can discuss in our
Recommended
Can genes create the perfect diet for you?
Diet on genotype can be a way out for many, but it still has a lot of questions Don't know what to do to lose weight? DNA tests promise to help you with this. They will be able to develop the most individual diet, because for this they will use the m...
How many extraterrestrial civilizations can exist nearby?
If aliens exist, why don't we "hear" them? In the 12th episode of Cosmos, which aired on December 14, 1980, co-author and host Carl Sagan introduced viewers to the same equation of astronomer Frank Drake. Using it, he calculated the potential number ...
Why does the most poisonous plant in the world cause severe pain?
The pain caused to humans by the Gimpi-gympie plant can drive him crazy Many people consider Australia a very dangerous place full of poisonous creatures. And this is a perfectly correct idea, because this continent literally wants to kill everyone w...
Related News
As the coat color of Labrador affects their life expectancy?
the Study, which was published in the journal Canine Genetics and Epidemiology, has shown that chocolate Labrador retrievers often experience health problems and die faster than dogs of the same breed, but with a different coat co...
Discovered the "switch" pleasure from alcohol
One of the key factors of addiction mechanisms in the brain is obtaining positive emotions. For example, the alcohol getting to the brain, affects the ventral tegmental area (ventral tegmental area, VTA), also called the pleasure ...
Ten predictions of Hawking, which he left in the book after his death
the Latest work of Stephen Hawking, which deals with such problems as the existence of God or the possibility of time travel, was presented on Monday his children who tried to finish the book after the death of the British giant o...
New product effectively solves the problem of lack of oxygen in the blood
Oxygen — the basis of our life. There are more susceptible to the lack of tissue is less sensitive. But in any case, the lack of this important element of the authorities (and then entire body) will not last long. In case of...
Under the surface of Mars may be enough oxygen for life
the Ability to find life on Mars has troubled scientists for many years, and recent discoveries only increased the excitement on the subject, we find, at last, life on the red planet or not. And now, a new study in Nature Geoscien...
Gravitational waves may shed light on dark matter
the Future Laser interferometric space antenna (LISA) will be a powerful tool that will allow astronomers to study phenomena such as colliding black holes and gravitational waves moving through space-time. Scientists from the Univ...
Scientists in Australia have discovered a new genetic disease
Daily scientists are looking for methods to combat various diseases. But unfortunately, a new disease is also sometimes found. And, as reported by the editorial Board Еurekalert, recently a group of scientists from the Australian ...
How virtual reality affects the taste of the food
Virtual reality allows us to feel like we are in a completely different world. In advanced helmets sensations sometimes so real that you don't even pay attention to graphics and completely immersed in a fictional world on the othe...
Scientists "reprogrammed" the immune system to fight cancer
unfortunately, almost all drugs have, in addition to therapeutic effect, and even negative impact on the body. And the best cure mechanism — with the help of our own immune system. But the immune system is not all-powerful a...
From what fell "Union"? The investigation found guilty
11 October, the planned launch of "Soyuz-MS-10" with the carrier rocket "Soyuz-FG". But to reach orbit failed. Crash is the separation of the side blocks of the first stage from the Central block of the second stage. Then triggere...
On the Ground find pieces of Mars. How they got here?
When the planets revolve around the Sun, separated by a good distance, we think that they are not in contact and share material. The solar system can be a cruel place, where asteroids are falling and flying comets, but the planets...
Scientists from MIT said that could be responsible for the development of intelligence
Despite the fact that the nervous system of humans and other mammals already studied well enough how some of its aspects still remains a mystery. For example, if we compare the structure of the brain of humans and our closest of k...
Biologists have found a way to create plants that can survive on other planets
the Construction of a colony of Earthmen outside of our planet rests on one very serious problem: the lack of resources for food, agriculture and, of course, oxygen. All these problems could be solved if the earth's flora can grow...
If you didn't know: what is the difference between a comet and an asteroid?
In our Solar system there are many things that revolve around the Sun — that is, are in his orbit. The earth goes around the Sun for 365 days. Seven other planets also go around the Sun together with its satellites, and together w...
Could a Large Gap to cause a new Big Bang?
There are several issues that will not allow us to sleep at night, and they relate to the ultimate destiny of the whole cosmos. The stars light up, replace them with new, they too fade, and all is repeated until the Universe runs ...
Confirmed: the Earth's inner core solid
a New study conducted by researchers from the Australian national University (ANU) can help us understand how our planet was formed. Associate Professor, Hrvoje, Tkalcic and Dr. Thanh-Pham Sleep sure that proved that the Earth's i...
Scientists have shown what happens when a drone will collide with a plane
a Team of scientists from the research Institute of the University of Daytona has created a video, which showed what can happen with the aircraft when it collides with an unmanned aerial vehicle, or simply a drone. The results of ...
Imaging proved that dogs really do understand human speech
dog Owners surely at least once it seemed that their Pets understand the meaning of certain words. There is a high probability that these guesses were true — a study by researchers from Emory University have proved that dogs can a...
Astronomers have discovered the largest and heaviest object in the early Universe
Scientists from the National astrophysics Institute of Italy in Bologna to announce the opening of the largest and the heaviest of the object of the early Universe – a huge superclusters of galaxies located 11 billion light-years ...
Adequate consumption of vitamins and minerals can ensure a healthy longevity
According to scientists from the research Institute at children's hospital in Oakland (USA), published in the journal MedicalXpress, about 70% of the population of most developed countries having problems with food, have a lack of...
Comments (0)
This article has no comment, be the first!