Russian scientists have slowed the aging of cells using the sleep hormone

Date:

2017-02-11 07:30:05

Views:

713

Rating:

1Like 0Dislike

Share:

Russian scientists have slowed the aging of cells using the sleep hormone

Anti-aging is one of the leading places in cosmetology and medicine. And if to correct symptoms of aging is not difficult, to slow down the process «inside» at times more difficult. And according to the journal Biochimica et Biophysica Acta, recently scientists of the Institute of theoretical and experimental Biophysics RAS found a way to slow the aging process with the help of the sleep hormone melatonin.

As is known, a major role in the aging process play mitochondria. These complex structures have their own DNA and are sort of «power plants» the cells of our body to provide energy in the form of ATP. When the mitochondria begin to work intermittently, there are a number of pathologies that lead to aging. Until now it was believed that these diseases arise due to mutations in the mitochondrial DNA, which cannot be reversed, but it was not.

A Group of scientists led by Oleg Krestinin found that the above mentioned process is not associated with mutations. The reason is violation in the structure of mitochondria, and this process can be slowed down with the help of melatonin. Melatonin — it is a sleep hormone. He is responsible for the processes of sleep and waking, and is a powerful antioxidant. But scientists drew another property of the hormone: the fact that its concentration in the human body with age gradually reduced, what caused the sleepiness of the elderly. The researchers decided to find out whether these processes the relationship.

«age «power plant» the cells become more «leaky» they appear pores through which mitochondria are leaving «unnecessary» calcium ions build up inside them due to the fact that older mitochondria worse cope with stress and the emergence of aggressive molecules within its limits. This process eventually leads to the destruction of mitochondria, and triggering the suicide program of the cell. In our experiments on mitochondria isolated from rat liver, we showed that prolonged use of melatonin promotes the closure of pores in the mitochondria and prevents the escape of the enzymes. Continuous administration of melatonin, even in old animals improves mitochondrial function».

As shown by experiments on the cells of rats and mice, the addition of melatonin actually protects mitochondria and maintains within them are important enzymes responsible for the cycle of the Assembly of ATP, which prevents «unnecessary» molecules, aging and cell death.

Recommended

Crafted bracelet is predicting bouts of anger

Crafted bracelet is predicting bouts of anger

Autism more common in boys than in girls. Autism is a fairly common disease, which affects one in 160 children worldwide. This disorder arises from disturbances in the development of the brain and is mainly characterized by the silence of a child and...

Is there a floor in our brain?

Is there a floor in our brain?

is There a difference between the brains of men and women? If there are any intellectual differences, sex-linked? Why do the sexes often perceive exactly the same life situation in different ways? All of these questions answers is a special science ...

Of mental illness are directly related to environmental pollution

Of mental illness are directly related to environmental pollution

People suffer from depression even if you become rich What is necessary for each person to be happy, peaceful and satisfied life? Perhaps the answer here may be obvious: each of us need health, money and meeting the demand for recognition and love. W...

Comments (0)

This article has no comment, be the first!

Add comment

Related News

Created by a prosthesis controlled by signals of nerves in the spinal cord

Created by a prosthesis controlled by signals of nerves in the spinal cord

Scientists from Imperial College London have developed that interprets the signals of the nerve endings of the spinal cord and turns them into movements of the prosthetic hand. To lead hand in motion, a person only need to think a...

Chocolate tablet save you from dementia, heart attack and stroke

Chocolate tablet save you from dementia, heart attack and stroke

Long known that the disease is easier to prevent than to treat. Diagnostic and preventive medicine in the world pays a lot of attention. And in the prevention of diseases, a role played by proper nutrition. Often unusual useful pr...

Created a subcutaneous implant is a neuromodulator, which will save you from obesity

Created a subcutaneous implant is a neuromodulator, which will save you from obesity

the Extra weight gives people a lot of problems. In addition to the purely aesthetic, obesity leads to increased risk of a number of diseases. That is why the fight against this condition is actively conducted worldwide. Undoubted...