New drug to fight superbugs as "a Trojan horse"

Date:

2018-10-30 15:15:06

Views:

91

Rating:

1Like 0Dislike

Share:

New drug to fight superbugs as

In recent years, the number of superbugs (in other words, bacteria resistant to almost all known antibiotics) are becoming more and more. And this is in fact a real problem that need to do something. The obvious conclusion — to develop a "superactivity". But there is another method, which the authors call a "Trojan horse in the fight against superbugs".

As the publication of the New Atlas, a new drug called refigerator and at the moment he is already undergoing clinical trials. Moreover, the action of the drug rather elegant way. The main mechanism of action is based on the fact that many superbugs need for iron to sustain life processes. It is this vulnerability of the drug and "uses"

"Refigerator uses a new mechanism of penetration into the cell. It binds with the iron, penetrates with him inside the bacteria and destroys it from the inside." — said lead author of the project Simon Portsmouth.

This drug has successfully completed phase three trials, the last of which was with the participation of 448 patients with complicated urinary tract infections. Efficacy compared with a combination of antibiotics imipenem and cilastatin. It turned out that refigerator not only not inferior to the combination of drugs, but also causes much less side effects.

"the results are extremely important, because at the moment we have in the Arsenal, very few drugs against superbugs. As we found out, now refigerator has the highest effectiveness against gram-negative microorganisms."

If the results are confirmed by further tests — he'll get approval from Management on sanitary inspection behind quality of foodstuff and medicines USA (FDA), and therefore the output of the drug on the market will be held in the near future.

Recommended

Scientists are developing a unique painkiller

Scientists are developing a unique painkiller

In Morocco is growing kaktusovoda plant Euphorbia resinifera (resin spurge) which contains the active substance resiniferatoxin. According to the Scoville scale, this substance is 16 billion units. For comparison, this is 10 000 times more than the "...

"Meat from a test tube" has been approved in the United States

Literally on Friday U.S. authorities have agreed on how to regulate food product, cultivated from animal cells. It paves the way for the so-called "meat from a test tube" at the American plates. And look, we have to come, too, if history moves in spi...

New test helps predict how smart is the child before its birth

New test helps predict how smart is the child before its birth

It's not really a well-known fact, but still in the procedure of in vitro fertilization (IVF) the parents have the opportunity to choose from several embryos that continue to develop into a full organism. Of course, before that, scientists will carry...

Comments (0)

This article has no comment, be the first!

Add comment

Related News

CRISPR opens the way for a new method of treatment —

CRISPR opens the way for a new method of treatment — "genomic surgery"

the Notorious editor of the CRISPR-Cas9 was a breakthrough in genetics. With his help I made a few discoveries. It also marked the beginning of the phenomenon of "gene therapy". However, the group of doctors from the University of...

Discovered structure, with a large regenerative potential than stem cells

Discovered structure, with a large regenerative potential than stem cells

Stem cells have long (and very successfully) used in the so-called regenerative medicine. However, as it turned out, there is in our body and better structures that will give a new impetus to the development of new technologies fo...

NASA tested a parachute for landing on Mars

NASA tested a parachute for landing on Mars

At the moment the American space Agency NASA have been preparing for the Mars 2020 mission. Through the planned series of tests recently completed the third (and final) stage of testing of the parachute system ASPIRE (Advanced Sup...