Dragons will help in the production of antibiotics

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2017-04-17 17:00:05

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Dragons will help in the production of antibiotics

In recent years, the uncontrolled use of antibiotics provoked the development of resistance to antibacterial therapy of microbial strains. This important issue is forcing pharmaceutical companies around the world to develop new and more sophisticated types of antibiotics, while «raw» for the production of often very non-standard. According to the publication NPJ Biofilms and Microbiomes, the substances contained in the blood Komodo dragon (also known as the Komodo Dragon, or just dragon) can help professionals in the creation of antibacterial drugs of a new type.

Komodo dragon — is one of the biggest on the planet are species of lizards that inhabits the Indonesian Islands: Rinca, Flores, Gili Motang Padar and Komodo (in honor of the last island of the lizard got its name). Komodo can have a body length of three meters.

A Team of experts from George Mason University, in Manassas, Virginia by studying the activity of giant reptiles, were able to establish that these lizards very rarely get sick. Thus it is surprising that the Komodo dragon eats large amounts of rotten meat and saliva of a dragon is literally teeming with pathogenic bacteria. This led researchers to believe that the immune system of reptiles may have unique properties.

May this great lizards themselves without realizing it, in the future will be able to save more than one life

According to experts, this resistance is due to a peptide molecule called VK25. It is contained in a high enough concentration in the blood is secreted, and by analyzing this connection, the scientists came to the conclusion that the peptide is able to resist bacteria. "Rebuild" a few amino acids in the peptide composition of the team was able to create a synthetic version VK25, called all drgn-1. As a result, the connection is even more effective to fight bacteria.

The tool was Tested on mice, the wounds which were infected of antibiotic-resistant strains of Staphylococcus aureus and Pseudomonas aeruginosa. All drgn peptide-1 destroyed the biofilm (compounds that form conglomerates of bacteria on surface wounds) infection of rodents and destroyed microorganisms. Scientists hope that drugs based on new compound can become a new strong antibiotic.

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